Acute Myelogenous Leukemia (AML)

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Summary

Acute myelogenous Leukemia, or AML for short, is a myeloblast neoplasm. These myeloblast cells can be identified using an immunohistochemical stain for myeloperoxidase. AML occurs primarily in older patients, and presents with a triad of fatigue, recurrent infections, and easy bleeding. These symptoms reflect the underlying anemia, leukopenia, and thrombocytopenia that result from the bone marrow being overcrowded by myeloblasts. There are several important risk factors for AML, including prior chemotherapy or radiation exposure, myeloproliferative disorders, or down syndrome.