USMLE

Immunoglobulin D (IgD)

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Immunoglobulins
  1. Immunoglobulin A (IgA)
  2. Immunoglobulin G (IgG)
  3. Immunoglobulin M (IgM)
  4. Immunoglobulin E (IgE)
  5. Immunoglobulin D (IgD)

Summary

Immunoglobulin D (IgD) is an antibody with poorly understood functions. It is expressed on the surface of B-cells as a B-cell receptor for antigens.

Key Points

  • Immunoglobulin D (IgD) 
    • Unclear function
      • Co-expressed with lgM as a B-cell Receptor
      • Low levels circulate in serum