Scopolamine

1561

Summary

Scopolamine is a centrally acting muscarinic antagonist that blocks central M1 receptors to help treat motion sickness.

Key Points

  • Scopolamine
    • Mechanism
      • Muscarinic Antagonist
        • Blocks M1 Muscarinic Receptors in CNS
    • Clinical Use
      • Motion sickness (vestibular nausea)
        • Scopolamine patches are widely prescribed to treat seasickness or secondary causes of vestibular nausea (e.g. Meniere’s disease)