Medicine

/

USMLE Step 1

/

Onc Drugs (in-progress)

Previous
Next

Cetuximab, Panitumumab

212
Watch Video

Summary

Cetuximab and panitumumab are monoclonal antibodies against EGFR and are used to treat stage IV colorectal cancer and head and neck cancers. Patients on cetuximab and panitumumab may experience elevated LFTs, rash, and diarrhea as side effects. 

Key Points

  • Cetuximab / Panitumumab
    • Mechanism
      • Monoclonal antibody against EGFR
    • Clinical use
      • Stage IV colorectal cancer
        • Wild-type KRAS
      • Head and neck cancers
    • Adverse effects
      • Elevated LFTs
      • Rash
      • Diarrhea