Ciguatoxin (Ciguatera Fish Poisoning)
Ciguatoxin, the causative agent behind ciguatera fish poisoning, is a foodborne toxin found in the flesh of contaminated reef fish.
The toxin exerts its effects by opening sodium channels in neurons, causing persistent depolarization that inhibits action potentials. This causes muscle weakness and bradycardia. Acute symptoms include GI disturbances with vomiting and diarrhea.
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