Medicine & USMLE

Yolk Sac Tumor

12,607 views
Misc
  1. Osteosarcoma
  2. McCune-Albright Syndrome
  3. Hexokinase vs Glucokinase
  4. COP I & II and Clathrin
  5. Kartagener Syndrome (Primary Ciliary Dyskinesia)
  6. Familial Adenomatous Polyposis (FAP)
  7. Peutz-Jeghers Syndrome
  8. Cystic Fibrosis Overview
  9. Cystic Fibrosis Complications
  10. Medicare vs Medicaid
  11. Duchenne and Becker Muscular Dystrophy
  12. Yolk Sac Tumor
  13. Rett Syndrome
  14. Fragile X Syndrome
  15. Whipple's Disease
  16. Osteoid Osteoma vs Osteoblastoma
  17. T1 vs T2 MRIs

Yolk sac tumors are aggressive germ cell tumors that often arise in young children. On gross pathology, these tumors have a yellow, friable appearance, and hemorrhage is common. Under the microscope, Schiller-Duval bodies resembling glomeruli may be seen—a finding that pathognomonic for yolk sac tumor. Labs will reveal an elevated level of AFP, as AFP is secreted by yolk sac cells.