Vitamin K Biochemistry
Vitamin K is a fat-soluble vitamin that is synthesized by the intestinal flora.
It is first activated by vitamin K epoxide reductase, after which it can participate as a cofactor for the gamma-carboxylation of glutamic acid residues on various blood clotting proteins. Therefore, Vitamin K plays an important role in coagulation, as there are a number of such vitamin K-dependent coagulation factors: factors II, VII, IX, X, as well as protein C and S.
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