Medicine & USMLE

Nebivolol

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Alpha & Beta Blockers (New)
  1. Phentolamine
  2. Phenoxybenzamine
  3. -osin Drugs
  4. Beta-1 Selective Beta Blockers
  5. Non-Selective Beta Blockers
  6. Dual Alpha Beta Blockers
  7. Nebivolol
  8. Clinical Use of Beta Blockers
  9. Side Effects of Beta Blockers

Summary

Nebivolol is a beta blocker medication. Like other beta blockers, it blocks beta-1 receptors in the heart. However, nebivolol is unique because it also activates beta-3 receptors in blood vessels.

Key Points

  • Nebivolol
    • Mechanism
      • Blocks Beta-1 receptors
        • Decreases heart rate and contractility → lowered cardiac output
      • Stimulates Beta-3 receptors
        • Increases Nitric Oxide (NO) production → causes vasodilation, which can lower blood presure