Dual Alpha Beta Blockers
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Alpha & Beta Blockers (New)
- Phentolamine
- Phenoxybenzamine
- -osin Drugs
- Beta-1 Selective Beta Blockers
- Non-Selective Beta Blockers
- Dual Alpha Beta Blockers
- Nebivolol
- Clinical Use of Beta Blockers
- Side Effects of Beta Blockers
Summary
The dual alpha-beta blockers are a subclass of beta blockers. They work as antagonists at alpha-1 receptors, beta-1 receptors, and beta-2 receptors. The two main drugs in this class are labetalol and carvedilol.
Key Points
- Dual Alpha and Beta Blockers
- Drug Names
- Carvedilol
- Labetalol
- Mechanism
- Blocks Alpha-1 Receptors
- Alpha 1 Blockade → Decreased vasoconstriction → Decreased TPR → Decreased BP
- Blocks Beta-1 Receptors
- Decreased HR (Chronotropy and Dromotropy) and Stroke Volume (Inotropy) → Decreased Cardiac Output
- Blocks Beta-2 Receptors
- Bronchoconstriction, Vasoconstriction
- Blocks Alpha-1 Receptors
- Drug Names