Milrinone
33 views
Cardio Drugs - Other
- Nitrates (Nitroglycerin, Isosorbide)
- Nitroglycerin Administration
- Digoxin Overview
- Digoxin Toxicity
- Ranolazine
- Milrinone
- Epinephrine
- Norepinephrine
- Dopamine
- Dobutamine
- Isoproterenol
- Atropine
Summary
Milrinone is a PDE inhibitor that works by causing positive inotropy and vasodilation.
It is used to treat heart failure, but is only recommended for short term use due to its potential side effects.
These side effects include hypotension and arrhythmias.
Key Points
- Milrinone (Primacor)
- Drug Class
- Phosphodiesterase Inhibitor
- Milrinone is a phosphodiesterase-3 inhibitor
- Phosphodiesterase Inhibitor
- Mechanism
- Positive inotrope (increases contractility)
- Vasodilation
- Relaxes the smooth muscle in the blood vessel walls
- Clinical Use
- Heart failure
- Only for short-term use
- Last resort medication
- Heart failure
- Side Effects
- Hypotension
- Closely monitor blood pressure during administration
- Arrhythmias
- Closely monitor cardiac rhythm during administration
- Hypotension
- Drug Class