Medicine & USMLE

Isoproterenol

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Cardio Drugs - Other
  1. Nitrates (Nitroglycerin, Isosorbide)
  2. Nitroglycerin Administration
  3. Digoxin Overview
  4. Digoxin Toxicity
  5. Dopamine
  6. Ranolazine
  7. Milrinone
  8. Epinephrine
  9. Norepinephrine
  10. Dobutamine
  11. Isoproterenol
  12. Atropine

Summary

Isoproterenol is an adrenergic agonist. It activates beta-1 receptors, which increases the heart rate. It also activates beta-2 receptors, which causes bronchodilation.

Isoproterenol is used to treat heart block, torsades de pointes, bradycardia, and cardiogenic shock.

Side effects of isoproterenol include tachycardia, and chest pain.

Key Points

  • Isoproterenol (Isuprel)
    • Mechanism
      • Adrenergic Agonist
        • Activates Beta-1 Receptors
          • Increases heart rate
        • Activates Beta-2 Receptors
          • Causes bronchodilation
    • Clinical Use
      • Treats bradycardia
        • Stimulating beta-1 receptors increases the heart rate, making it effective in treating bradycardia
      • Treats heart block
        • Isoproterenol improves cardiac conduction through the AV node
      • Treats cardiogenic shock
        • Stimulating beta receptors increases the heart’s rate and contractility, thereby improving cases of cardiogenic shock
      • Treats torsades de pointes
        • Stabilizes cardiac electrical conduction, helping the heart return to a normal rhythm
    • Side Effects
      • Angina
      • Tachycardia
      • Arrhythmias
      • Tachycardia
      • Headache
      • Restlessness